Actin is a highly abundant protein that controls the shape and movement of all our cells. Actin achieves this by assembling into filaments, one actin molecule at a time. The proteins of the formin ...

Their work, published in Nature Communications, reveals a mechanism of interdependence of different forms of the cytoskeletal proteins actin and myosin, and their functions. The team also ...

Our skin and mucous membranes are protected by epithelial cells, which form a barrier that defends the body from the outside ...

Actin filaments are the smallest type, with a diameter of only about 6 nm, and they are made of a protein called actin. Intermediate filaments, as their name suggests, are mid-sized, with a ...

The paper S. Kaur et al., “An unmet actin requirement explains the mitotic inhibition of clathrin-mediated endocytosis,” eLife, 3:e00829, 2014. For decades, scientists observed clathrin-mediated ...

The bacterial protein identified by the team, which they have named BeeR, has a similar function to actin—the most abundant protein in the majority of human cells. In the presence of a chemical ...

(A) In a cell, motility is initiated by an actin-dependent protrusion of the cell’s leading edge, which is composed of armlike structures called lamellipodia and filopodia. These protrusive ...

This was followed by a post-doctoral work with David Drubin at UC Berkeley, USA focusing on actin dynamics in budding yeast. Since 1998, Pekka has been a group leader at Institute of Biotechnology, ...

Calcium signaling helps immune cells spread. Neutrophils are immune cells that travel through tissues to fight infections. Their ability to reach sites of infection depends on cel ...