The renin-angiotensin-aldosterone system (RAAS) is now known to play a key role in the pathogenesis of hypertension and a range of other cardiovascular diseases. Two groups of drugs, the ACE ...

Role of the RAAS in the Pathophysiology of Heart Failure ACE inhibitors have no effect on angiotensin II formed by alternate pathways. In contrast, ARBs would be expected to inhibit the biologic ...

However, at doses achieving the same blood pressure, RAAS inhibitors, such as angiotensin-converting-enzyme (ACE) inhibitors and ARBs, reduce proteinuria further than non-RAAS-inhibiting drugs, an ...

These agents include angiotensin-converting-enzyme (ACE) inhibitors, angiotensin-receptor blockers (ARBs), mineralocorticoid-receptor antagonists, and direct renin inhibitors, all of which can ...

Many people diagnosed with hypertension are prescribed angiotensin-converting enzyme inhibitors—better known as ACE-1 ...

High blood pressure, or hypertension, affects more than a billion people worldwide and remains the leading cause of death due ...

Before receiving a kidney transplant, patients with autosomal dominant polycystic kidney disease often undergo a nephrectomy. But there hasn’t been clear guidance on who’s a good candidate ...

Many of them are prescribed angiotensin-converting enzyme inhibitors—better known as ACE-1 inhibitors (ACEIs)—and/or angiotensin receptor blockers (ARBs), which act on the renin-angiotensin ...