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Hosted on MSN18d
Key mechanism behind prostate cancer drug resistance reveals potential new treatment strategy
In this study, researchers found that the molecule PLK1 promotes the degradation of PDCD4, causing the activation of a pathway that clears some drugs and promotes proliferation. "These results ...
Hosted on MSN27d
A starting signal for cell division: Molecular switch ensures that cells divide at the right time
More information: Monica Gobran et al, PLK1 inhibition delays mitotic entry revealing changes to the phosphoproteome of mammalian cells early in division, The EMBO Journal (2025). DOI: 10.1038 ...