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Clinical trials improve care and access to novel treatments for advanced gastrointestinal cancers, says Dr. Michael Pishvaian ...
An isogenic cell line was created to model cancer patients with the echinoderm microtubule-associated protein-like 4 (EML4)-anaplastic lymphoma kinase (ALK) fusion oncogene and tested for its ...
Enabling RNA-Based Applications: A single ALK fusion call supported fusion detection in one case, highlighting the method’s potential for RNA-based applications despite degradation. The method ...
How do ALK inhibitors work in cancer? In NSCLC-type cancer patients, a fusion of two genes—ALK and the EML4 gene in 90% of cases—results in a new gene capable of encoding a mutated protein and ...
In NSCLC-type cancer patients, a fusion of two genes — ALK and the EML4 gene in 90% of cases — results in a new gene capable of encoding a mutated protein and activating signalling pathways ...
BioIVT, a global research partner and biospecimen solutions provider for drug and diagnostic development, presented new data at the Precision Med TRI-CON conference. The data supports an innovative ...