for the antibody–drug conjugate (ADC) trastuzumab–DM1 (T–DM1). It is hoped that by coupling trastuzumab (Herceptin; Genentech/Roche) — a humanized monoclonal antibody (mAb) specific for ...

During the preclinical and clinical phases of ADC drug development ... now four more anti-payload antibodies being developed: anti-DM1 antibody, anti-DM4 antibody, anti-SN-38 antibody, and ...