The adrenocorticotrophic activity of pituitary extracts has been assayed principally by three methods, the first being that based on adrenal size . . . From the Medical Clinic, Peter Bent ...

ACTH insensitivity is a cardinal feature of ALD, but the mechanism is unknown. We studied a 10 year old hyperpigmented boy with glucocorticoid insufficiency of 8 years duration and a history of ...