Current biomarkers of cognitive impairment in individuals with Alzheimer’s disease perform poorly. Now, a stronger predictor ...

The team discovered that larger Aβ clumps trigger more myddosome formation in immune cells. Smaller Aβ clumps, even after longer exposure, failed to trigger this response. This suggests that the ...

Hardy and Higgins first postulated the amyloid hypothesis in 1991, and since then, amyloid β (Aβ) has been a central concept in understanding disease progression. Along with Aβ plaques ...