The researchers tested the compound in 5xFAD mice, a well-established model of Alzheimer’s disease, administering diAcCA for three months. The results were remarkable. Related Stories ・Common ...

The blood-brain barrier border protects the brain by regulating the flow of molecules, peptides, and cells, but it also keeps out many therapeutics. Now, researchers have harnessed the power of a ...

UB-SCG-74 was tested in 5XFAD mice—animals that quickly develop symptoms similar to human Alzheimer’s. The treated mice showed better memory, stronger synaptic plasticity (the ability of brain ...

Honours (2010 - 2011; with Dr. Heather Schellinck): The roles of the main and accessory olfactory systems in the maternal behaviour of mice. PhD (2015 to present): Mechanisms behind weight loss seen ...

New data in 5xFAD plaque-burdened mice illustrate that small molecule TREM2 agonism enhances microglial uptake of both Aβ and Tau supporting the broad efficacy potential of the TREM2 agonist ...