Researchers at The University of Manchester have discovered that a protein (5T4) found on the surface of cells contributes to chemotherapy resistance in the most common type of childhood leukaemia.

TUB-030 specifically targets the oncofoetal antigen 5T4, which is prevalent across a wide range of solid tumours. It leverages the company’s Tubutecan linker-payload platform, which has been ...

These include: (1) a poster presentation of Abdera’s ongoing Phase 1 clinical trial for ABD-147, a DLL3-targeting radiopharmaceutical, and (2) preclinical data on ABD-320, a 5T4-targeting ...