Microdosing psychedelics like LSD and psilocybin shows potential for enhancing mental health, creativity, and cognitive ...

A preclinical study from Northeastern University has revealed astonishing evidence that psilocybin – the psychedelic compound ...

DOI strongly activates certain receptors in the brain called 5-HT2A and 5-HT2C, which normally respond to the neurotransmitter serotonin, leading to altered perceptions, mood changes, enhanced ...

According to the partners, DSP-0038 combines serotonin 5-HT2A receptor antagonism and 5-HT1A receptor agonism – two well established targets for antipsychotic drugs – in a single small molecule.

Axovant turned its attention to another neuroscience drug – 5-HT2A receptor inverse agonist nelotanserin, licensed from Arena Pharma – but that failed a phase 2 study in REM sleep behaviour ...