In the second step, the AMP is transferred to the 5’-end of the 5’-phosphate-terminated DNA strand to form DNA-adenylate — an inverted pyrophosphate bridge structure, AppN. In this reaction, the ...

The newly synthesized DNA (light blue) can then be joined with the 5' end of the resected strand, forming a double Holliday junction (double-strand break repair; DSBR), or can be displaced and ...