RBP3 plays a key role in delivering all-trans-retinol (at-ROL) from photoreceptors to the retinal pigment epithelium, where it is converted into 11-cis-retinal (11c-RAL), a key molecule for vision.

Darwinian evolution says that complex systems arise through numerous successive, slight modifications that benefit the species' survival over many generations. However, we have shown that bacterial ...

A ligand dose–response curve with the photoactivatable agonist 11-cis-retinal showed a half-maximal signal at 120 nM. Our findings may be useful to develop novel assay formats for GPCRs based on ...